Great Review Quizzes! - Skip Quiz #4
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DNA Structure:
Cyberbridge Reading
Biology Corner
Bozeman Science - Nucleic Acids: http://www.bozemanscience.com/nucleic-acids
Ms. Castle - DNA vs RNA: https://www.youtube.com/watch?v=_lK-ZKfUJA8&index=3&list=PLb1wF0xa6WI-4EWCe6xmPwBAfdJhW_A3J
Bozeman Science - DNA and RNA: http://www.bozemanscience.com/027-part-1-dna-rna
Bozeman Science - Meselson and Stahl Experiment: http://www.bozemanscience.com/meselson-stahl-experiment
DNA Replication:
Biology Corner
Harvard Education Site
Crash Course Biology - DNA Structure and Replication: https://www.youtube.com/watch?v=8kK2zwjRV0M
Ms. Castle - Semi-conservative DNA Replication: https://www.youtube.com/watch?v=FHsYGWL-b-Q&index=4&list=PLb1wF0xa6WI-4EWCe6xmPwBAfdJhW_A3J
Ms. Castle - Enzymes in DNA Replication: https://www.youtube.com/watch?v=K0SC06djG04&index=5&list=PLb1wF0xa6WI-4EWCe6xmPwBAfdJhW_A3J
Bozeman Science - DNA Replication: http://www.bozemanscience.com/dna-replication/
Central Dogma (Transcription and Translation):
St. Olaf College animates Transcription
Harvard Education Site explains Translation
Interactive animation of Transcription and Translation
Bozeman Biology: http://www.bozemanscience.com/transcription-translation/
Crash Course Biology: https://www.youtube.com/watch?v=itsb2SqR-R0
Ms. Castle - Transcription: https://www.youtube.com/watch?v=kjRd-BLKJzQ&index=6&list=PLb1wF0xa6WI-4EWCe6xmPwBAfdJhW_A3J
Ms. Castle - Translation: https://www.youtube.com/watch?v=EDR5xJ0Kov8&index=7&list=PLb1wF0xa6WI-4EWCe6xmPwBAfdJhW_A3J
Amoeba Sisters explain Protein Synthesis
Gene Regulation
Bozeman Science explains Operons and Enhancers
Bozeman Science explains Epigenetics
Crash Course on Epigenetics
NOVA explains Epigenetics
A little bit of everything (Good Review):
Bozeman Science: http://www.bozemanscience.com/027-part-2-dna-rna
Cyberbridge Reading
Biology Corner
Bozeman Science - Nucleic Acids: http://www.bozemanscience.com/nucleic-acids
Ms. Castle - DNA vs RNA: https://www.youtube.com/watch?v=_lK-ZKfUJA8&index=3&list=PLb1wF0xa6WI-4EWCe6xmPwBAfdJhW_A3J
Bozeman Science - DNA and RNA: http://www.bozemanscience.com/027-part-1-dna-rna
Bozeman Science - Meselson and Stahl Experiment: http://www.bozemanscience.com/meselson-stahl-experiment
DNA Replication:
Biology Corner
Harvard Education Site
Crash Course Biology - DNA Structure and Replication: https://www.youtube.com/watch?v=8kK2zwjRV0M
Ms. Castle - Semi-conservative DNA Replication: https://www.youtube.com/watch?v=FHsYGWL-b-Q&index=4&list=PLb1wF0xa6WI-4EWCe6xmPwBAfdJhW_A3J
Ms. Castle - Enzymes in DNA Replication: https://www.youtube.com/watch?v=K0SC06djG04&index=5&list=PLb1wF0xa6WI-4EWCe6xmPwBAfdJhW_A3J
Bozeman Science - DNA Replication: http://www.bozemanscience.com/dna-replication/
Central Dogma (Transcription and Translation):
St. Olaf College animates Transcription
Harvard Education Site explains Translation
Interactive animation of Transcription and Translation
Bozeman Biology: http://www.bozemanscience.com/transcription-translation/
Crash Course Biology: https://www.youtube.com/watch?v=itsb2SqR-R0
Ms. Castle - Transcription: https://www.youtube.com/watch?v=kjRd-BLKJzQ&index=6&list=PLb1wF0xa6WI-4EWCe6xmPwBAfdJhW_A3J
Ms. Castle - Translation: https://www.youtube.com/watch?v=EDR5xJ0Kov8&index=7&list=PLb1wF0xa6WI-4EWCe6xmPwBAfdJhW_A3J
Amoeba Sisters explain Protein Synthesis
Gene Regulation
Bozeman Science explains Operons and Enhancers
Bozeman Science explains Epigenetics
Crash Course on Epigenetics
NOVA explains Epigenetics
A little bit of everything (Good Review):
Bozeman Science: http://www.bozemanscience.com/027-part-2-dna-rna
Chromosome Number Activity
Click the links on each of the binomial names below to find out the genome size of these species and to compare diploid chromosome numbers.
Genome Browser links for five species
Homo sapiens, Pan troglodytes, Canis familiaris, Oryza sativa, Drosophila melanogaster,
The hyperlinks on each name link to the karyotype page in the Ensembl.org database search engine from Wellcome Sanger.
Complete the Genome size and chromosome number activity.
http://www.ncbi.nlm.nih.gov/genome/browse/ --> This page can be used to find the genome sizes in the guide
http://www.ensembl.org --> This is a better genome browser. You can even zoom in to see base pairs. It has plant and invertebrate species on http://ensemblgenomes.org/
Click the links on each of the binomial names below to find out the genome size of these species and to compare diploid chromosome numbers.
Genome Browser links for five species
Homo sapiens, Pan troglodytes, Canis familiaris, Oryza sativa, Drosophila melanogaster,
The hyperlinks on each name link to the karyotype page in the Ensembl.org database search engine from Wellcome Sanger.
Complete the Genome size and chromosome number activity.
http://www.ncbi.nlm.nih.gov/genome/browse/ --> This page can be used to find the genome sizes in the guide
http://www.ensembl.org --> This is a better genome browser. You can even zoom in to see base pairs. It has plant and invertebrate species on http://ensemblgenomes.org/
John Cairns and Autoradiography
These diagrams illustrate how models, based on theoretical understanding, are developed to explain processes that may not be observable or to make testable predictions. The diagram on the left shows a diagrammatic representation of the theory of DNA replication in prokaryote chromosomes and the autoradiograph on the right shows a molecule of E.coli DNA. Autoradiography became an essential tool in gene sequencing in the 1980s and is still in use today in a modified form in genetic labs around the world.
Images: CSHL Symposium 1963
In his 1963 paper "The bacterial chromosome and its manner of replication as seen by autoradiography", Cairns demonstrated by autoradiography that the DNA of the bacterium Escherichia coli was a single molecule that is replicated at a moving locus (the replicating fork) at which both new DNA strands are being synthesized.
http://samsonlab.mit.edu/cairns.html
When interviewed about these experiments Cairns commented, "I said to myself, I know about autoradiography, why don’t I see if I can measure the length of these molecules using this technique? And did some little calculation and decided that it should be possible and only will take two months under film. And that's what I did at Cold Spring Harbour"
These diagrams illustrate how models, based on theoretical understanding, are developed to explain processes that may not be observable or to make testable predictions. The diagram on the left shows a diagrammatic representation of the theory of DNA replication in prokaryote chromosomes and the autoradiograph on the right shows a molecule of E.coli DNA. Autoradiography became an essential tool in gene sequencing in the 1980s and is still in use today in a modified form in genetic labs around the world.
Images: CSHL Symposium 1963
In his 1963 paper "The bacterial chromosome and its manner of replication as seen by autoradiography", Cairns demonstrated by autoradiography that the DNA of the bacterium Escherichia coli was a single molecule that is replicated at a moving locus (the replicating fork) at which both new DNA strands are being synthesized.
http://samsonlab.mit.edu/cairns.html
When interviewed about these experiments Cairns commented, "I said to myself, I know about autoradiography, why don’t I see if I can measure the length of these molecules using this technique? And did some little calculation and decided that it should be possible and only will take two months under film. And that's what I did at Cold Spring Harbour"